Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Sox10-ERT2/cre/ERT2)17Sor
Name:	transgene insertion 17, Philippe Soriano
MGI ID:	MGI:5697877
Synonyms:	SECE17, Sox10ERT2CreERT2
Transgene:	Tg(Sox10-ERT2/cre/ERT2)17Sor  Location: unknown
Alliance:	Tg(Sox10-ERT2/cre/ERT2)17Sor page

Strain of Origin:

C57BL/6 x C3H

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Sox10-ERT2/cre/ERT2)17Sor expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Sox10   Mutation details: The Multiple Species Conserved Sequence 4 (MCS 4) distal enhancer with a c-Fos minimal promoter drives neural crest cell and derivatives-specific expression of an inducible cre recombinase gene flanked by two modified estrogen receptors (ERT2/cre/ERT2) followed by a rabbit globin polyadenylation sequence. Two lines were generated with line 17 selected as the representative line. (J:226186)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox10 (species not specified) Summary of all recombinase alleles driven by Sox10. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:226186 He F, et al., Sox10ER(T2) CreER(T2) mice enable tracing of distinct neural crest cell populations. Dev Dyn. 2015 Nov;244(11):1394-403
All:	1 reference(s)