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Gene Expression Data
Assay Details
Assay
Reference: J:225904 Zheng L, et al., Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation. Dev Dyn. 2015 Oct;244(10):1249-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5697515
Gene symbol: Orai1
Gene name: ORAI calcium release-activated calcium modulator 1
Antibody: anti-ORAI1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen E13 not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tooth Absent
Specimen E14 not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: tooth Absent
Specimen 1A,B: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: inner enamel epithelium Present 1B , 1A Expression mainly in internal enamel epithelium.
TS25: cervical loop Present Regionally restricted 1B , 1A Sporadic expression in cervical loop area.
TS25: enamel organ Present Regionally restricted 1B , 1A Expression mainly in preameloblastic cells.
TS25: dental papilla Present Spotted 1B , 1A Authors report sporadic expression in dental papilla.
Specimen 1C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: molar enamel organ Strong Regionally restricted 1C Strong expression in presecretory ameloblasts. Expression in stratum intermedium and young odontoblasts.
TS27: stratum intermedium Present 1C
Specimen 1D: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: molar enamel organ Strong Regionally restricted 1D Strong expression in presecretory ameloblasts. Expression in stratum intermedium and young odontoblasts.
TS27: stratum intermedium Present 1D
Specimen 1E,F: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: molar dental papilla Present Regionally restricted 1E , 1F Expression in both ameloblasts and odontoblasts.
TS28: molar enamel organ Present Regionally restricted 1E , 1F Expression in both ameloblasts and odontoblasts.
Specimen 1G: postnatal day 21 (more )
Note: Section at tip of incisor.
Structure Level Pattern Image Note
TS28: incisor enamel organ Present Regionally restricted 1G Expression in secretory and maturation ameloblasts.
Specimen 1H: postnatal day 21 (more )
Note: Section at middle of incisor.
Structure Level Pattern Image Note
TS28: incisor enamel organ Present Regionally restricted 1H Expression in secretory and maturation ameloblasts.
TS28: incisor dental papilla Present Regionally restricted 1H Expression in differentiated odontoblasts.
Specimen 1I: postnatal day 21 (more )
Note: Section at root of incisor.
Structure Level Pattern Image Note
TS28: incisor enamel organ Present Regionally restricted 1I Expression in secretory and maturation ameloblasts.
Specimen 1K: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 1K Expression on the cell membrane of mucous acini.
Specimen 1L: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: epidermis Present 1L
TS28: hair follicle Present 1L
Specimen 1M: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: oral epithelium Present Regionally restricted 1M Expression in stratified squamous nonkeratinized epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory