Gene Expression Data
Assay Details
Assay
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Reference:
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J:225414
Crisponi L, et al., The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. Nat Genet. 2001 Feb;27(2):159-66
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5697326
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Gene symbol:
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Foxl2
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Gene name:
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forkhead box L2
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Probe:
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Foxl2 probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5a (left):
embryonic day 14.5
(more )
Specimen
5a (left):
(close )
Genetic Background:
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FVB
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
5b:
embryonic day 14.5
(more )
Specimen
5b:
(close )
Genetic Background:
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FVB
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS22: eyelid |
Present |
Regionally restricted |
5b
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Expression in protruding ridges around cornea.
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Specimen
6a:
embryonic day 14.5
(more )
Specimen
6a:
(close )
Genetic Background:
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FVB
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS22: eye |
Strong |
Regionally restricted |
6a
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Strong expression all around optic cup.
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TS22: eyelid |
Strong |
Regionally restricted |
6a
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Higher level of expression in protruding ridges of eyelids.
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Specimen
6b:
embryonic day 14.5
(more )
Specimen
6b:
(close )
Genetic Background:
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FVB
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS22: perioptic mesenchyme |
Present |
Graded |
6b
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Expression is concentrated in perioptic mesenchyme and decreases in a sharp gradient.
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TS22: lens fiber |
Weak |
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6b
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Lower levels of expression in lens fibers.
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TS22: lower eyelid mesenchyme |
Present |
Regionally restricted |
6b
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Expression in lower eyelid in mesenchyme just below the epithelium, destined to form part of conjunctival sac.
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Specimen
7a,b:
postnatal adult
(more )
Specimen
7a,b:
(close )
Genetic Background:
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FVB
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Age:
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postnatal adult
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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