PolgGt(VET25A)Hiir
Gene trapped Allele Detail
|
Symbol: |
PolgGt(VET25A)Hiir |
Name: |
polymerase (DNA directed), gamma; gene trap VET25A, Takashi Hiiragi |
MGI ID: |
MGI:5696388 |
Gene: |
Polg Location: Chr7:79095979-79116110 bp, - strand Genetic Position: Chr7, 45.04 cM, cytoband E
|
Alliance: |
PolgGt(VET25A)Hiir page
|
|
|
Allele Type: |
|
Gene trapped |
Mutation: |
|
Insertion of gene trap vector
|
|
|
Mutation details: The lentiviral gene trap vector sinLV-pRRL-K contains a gene trapping splice acceptor; stop codons in all three reading frames; an internal ribosomal entry site (IRES); the Venus reporter gene with a nuclear localization signal; a woodchuck hepatitis post-transcriptional regulatory element (WPRE); central poly-purine tract (cPPT); Rev-responsive element (RRE); and Rous sarcoma virus promoter (RSV) all flanked by a self-inactivating lentiviral long terminal (LTR) consisting of U5, R and truncated U3 element (delta U3). The gene trap vector inserted into the 5'UTR of exon 1.
(J:224530)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Polg Mutation: |
57 strains or lines available
|
|
Original: |
J:224530 Dietrich JE, et al., Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep. 2015 Aug;16(8):1005-21 |
All: |
1 reference(s) |
|