Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Padi4tm1.2Kmow
Name:	peptidyl arginine deiminase, type IV; targeted mutation 1.2, Kerri A Mowen
MGI ID:	MGI:5695766
Synonyms:	Padi4fl
Gene:	Padi4  Location: Chr4:140473176-140501547 bp, - strand  Genetic Position: Chr4, 72.34 cM, cytoband E1
Alliance:	Padi4tm1.2Kmow page

Germline Transmission:	Earliest citation of germline transmission: J:174934
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site followed by an FRT-flanked neomycin resistance (neo) cassette upstream of exon 9, and a second loxP site downstream of exon 10. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 9 through 10 floxed. (J:174934)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Padi4 Mutation:	40 strains or lines available

Original:	J:174934 Hemmers S, et al., PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection. PLoS One. 2011;6(7):e22043
All:	18 reference(s)