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Casrtm1Mrpk
Targeted Allele Detail
Summary
Symbol: Casrtm1Mrpk
Name: calcium-sensing receptor; targeted mutation 1, Martin R Pollak
MGI ID: MGI:5695268
Synonyms: Casrflox
Gene: Casr  Location: Chr16:36314058-36382503 bp, - strand  Genetic Position: Chr16, 25.57 cM
Alliance: Casrtm1Mrpk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225084
Parent Cell Line:  C1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation details: A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. (J:225084)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Casr Mutation:  55 strains or lines available
References
Original:  J:225084 Toka HR, et al., Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol. 2012 Nov;23(11):1879-90
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory