Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wdr13tm1Kuma
Name:	WD repeat domain 13; targeted mutation 1, Satish Kumar
MGI ID:	MGI:5694710
Gene:	Wdr13  Location: ChrX:7989540-7999131 bp, - strand  Genetic Position: ChrX, 3.67 cM, cytoband A1.1
Alliance:	Wdr13tm1Kuma page

Germline Transmission:	Earliest citation of germline transmission: J:225111
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exon 2 and intron 2. Western blot analysis confirmed the absence of protein in testis and brain. (J:225111)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wdr13 Mutation:	11 strains or lines available

Original:	J:225111 Singh VP, et al., Lack of Wdr13 gene in mice leads to enhanced pancreatic beta cell proliferation, hyperinsulinemia and mild obesity. PLoS One. 2012;7(6):e38685
All:	6 reference(s)