Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnt1tm1.1Clin
Name:	potassium channel, subfamily T, member 1; targeted mutation 1.1, Christopher J Lingle
MGI ID:	MGI:5694636
Synonyms:	Slack floxed
Gene:	Kcnt1  Location: Chr2:25753807-25808285 bp, + strand  Genetic Position: Chr2, 18.27 cM
Alliance:	Kcnt1tm1.1Clin page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6 x 129X1/SvJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 11 and a second loxP site, followed by an FRT-flanked neomycin resistance (neo) cassette which includes a third loxP site, downstream of exon 11. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 11 floxed. (J:101977)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnt1 Mutation:	66 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	2 reference(s)