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Gene Expression Data
Assay Details
Assay
Reference: J:211189 Suzuki D, et al., Expression analysis of Dact1 in mice using a LacZ reporter. Gene Expr Patterns. 2014 May;15(1):21-30
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5694584
Gene symbol: Dact1
Gene name: dishevelled-binding antagonist of beta-catenin 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: cranial ganglion Strong 2A
TS20: dorsal root ganglion Strong 2A
TS20: inner ear Strong 2A
TS20: paramesonephric duct Strong 2A
TS20: heart Strong Regionally restricted 2A Expressed in the vessel wall and myocardium in the atrioventricular junction.
TS20: cardiac muscle tissue Strong Regionally restricted 2A Expressed in the myocardium in the atrioventricular junction.
TS20: body wall mesenchyme Strong Regionally restricted 2A Expressed in the abdominal wall mesenchyme.
TS20: mammary bud Strong Regionally restricted 2A Expressed in the nipple.
Specimen 2B: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: cranial ganglion Strong 2B
TS20: dorsal root ganglion Strong 2B
TS20: inner ear Strong 2B
TS20: paramesonephric duct Strong 2B
TS20: body wall mesenchyme Strong Regionally restricted 2B Expressed in the abdominal wall mesenchyme.
Specimen 2C: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: hindlimb mesenchyme Present Regionally restricted 2C Expressed in the mesenchyme of the wrists/ankles with a stronger signal in the anterior than posterior region.
Specimen 2E: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: cranial ganglion Strong 2E
Specimen 2F: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong 2F
TS20: heart Strong 2F
Specimen 2G: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: inner ear Present 2G
Specimen 2H: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 2H
Specimen 2I: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: heart Present Regionally restricted 2I Expressed in the vessel wall and myocardium in the atrioventricular junction.
TS20: cardiac muscle tissue Present Regionally restricted 2I Expressed in the myocardium in the atrioventricular junction.
Specimen 2J: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: tongue muscle Present 2J Expressed in the intrinsic muscle.
Specimen 2K: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present 2K
Specimen 2L: embryonic day 12.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS20: common bile duct Present Regionally restricted 2L Expressed in the mesenchyme surrounding the common bile duct.
Specimen 2M: embryonic day 14.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS22: mammary mesenchyme Present Regionally restricted 2M Expressed in the mesenchyme surrounding the nipple.
Specimen 2N: embryonic day 14.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS22: vomeronasal organ Present 2N
Specimen 2O: embryonic day 14.5; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS22: paramesonephric duct Strong 2O
TS22: nephric duct, mesonephric portion Absent 2O
Specimen 3A: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent 3A
TS28: midbrain Absent 3A
TS28: cerebellar cortex Strong 3A
TS28: cerebellum Weak 3A
TS28: medulla oblongata Weak 3A
Specimen 3B: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent 3B
TS28: pons Weak 3B
TS28: cerebral cortex Strong Regionally restricted 3B Expressed in the medial temporal lobes.
Specimen 3C: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent 3C
TS28: cerebral cortex Strong 3C
TS28: cerebellum Weak 3C
TS28: medulla oblongata Weak 3C
TS28: pons Weak 3C
Specimen 3D: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent 3D
TS28: midbrain Absent 3D
TS28: cerebellum Weak 3D
TS28: medulla oblongata Weak 3D
TS28: pons Weak 3D
TS28: cerebellar cortex Strong 3D
TS28: thalamus Strong 3D
TS28: hippocampus Strong 3D Strongest expression.
TS28: forebrain Strong Regionally restricted 3D Expressed in the ventral.
Specimen 3E: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 3E Strongest expression.
TS28: cerebral cortex Strong 3E
TS28: thalamus Strong 3E
Specimen 3G: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present Regionally restricted 3G Expressed in the cornu ammonis regions.
TS28: dentate gyrus granule cell layer Present 3G
TS28: hippocampus stratum radiatum Present 3G Expressed in some interneurons.
Specimen 3H: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present Regionally restricted 3H Expressed in all layers except for the outermost layer.
Specimen 3I: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: hippocampus stratum radiatum Present Widespread 3I Broadly expressed.
TS28: thalamus Present Widespread 3I Broadly expressed.
Specimen 3J: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: amygdaloid nucleus Strong 3J
TS28: piriform cortex Strong 3J
Specimen 3K: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present 3K
TS28: forebrain Present Regionally restricted 3K Expressed in the lateral orbital cortex in the ventral forebrain.
Specimen 5 bottom: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 5_bottom
TS28: photoreceptor layer Absent 5_bottom
TS28: retina inner nuclear layer Absent 5_bottom
TS28: retina inner plexiform layer Absent 5_bottom
TS28: retina outer nuclear layer Absent 5_bottom
TS28: retina outer plexiform layer Absent 5_bottom
Specimen 6A left: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: heart Strong Regionally restricted 6A left Expressed in the conotruncal region, including the connective tissue of the aortic valve and the muscle between elastic fibers in the aorta.
TS28: pulmonary artery Absent 6A left
Specimen 6C: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: aortic valve Present Regionally restricted 6C Expressed in the connective tissue.
TS28: aorta smooth muscle Present Regionally restricted 6C Expressed in the muscle between elastic fibers.
Specimen 7A left: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: testis Present 7A left
Specimen 7B left: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: oviduct Present 7B left
Specimen 7C left: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: endometrium Present 7C left
Specimen 7D: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: spermatid Present 7D Expressed in the late spermatids.
Specimen 7E: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: oviduct Present Regionally restricted 7E Expressed in a mosaic pattern in the connective tissue in the outer wall.
Specimen 7F: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: endometrium Present Uniform 7F
Specimen not shown: postnatal week 8; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: oocyte Absent
Specimen not shown: postnatal newborn; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS27: oviduct Present
TS27: uterus Present
Specimen not shown: postnatal day 0; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS27: aortic valve Present
TS27: aorta Present
Specimen not shown: postnatal day 1; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS27: oviduct Present
TS27: uterus Present
Specimen not shown: postnatal day 1; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS27: testis Absent
Specimen not shown: postnatal day 1; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present
TS27: photoreceptor layer Absent
TS27: retina inner nuclear layer Absent
TS27: retina inner plexiform layer Absent
TS27: retina outer nuclear layer Absent
TS27: retina outer plexiform layer Absent
Specimen not shown: postnatal day 7; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent
TS28: midbrain Absent
TS28: amygdaloid nucleus Present
TS28: anterior olfactory nucleus Present
TS28: cerebellar cortex Present
TS28: cerebellum Present
TS28: forebrain Present
TS28: hippocampus Present
TS28: medulla oblongata Present
TS28: piriform cortex Present
TS28: pons Present
TS28: thalamus Present
Specimen not shown: postnatal week 15; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present
TS28: photoreceptor layer Absent
TS28: retina inner nuclear layer Absent
TS28: retina inner plexiform layer Absent
TS28: retina outer nuclear layer Absent
TS28: retina outer plexiform layer Absent
Specimen not shown: postnatal week 35; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: spermatid Present
Specimen not shown: postnatal week 35; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: endometrium Present
TS28: oviduct Present
Specimen not shown: postnatal week 35; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: aortic valve Present
TS28: aorta smooth muscle Present
Specimen not shown: postnatal week 36; Dact1tm2b(EUCOMM)Hmgu/Dact1+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent
TS28: midbrain Absent
TS28: amygdaloid nucleus Present
TS28: anterior olfactory nucleus Present
TS28: cerebellar cortex Present
TS28: cerebellum Present
TS28: forebrain Present
TS28: hippocampus Present
TS28: medulla oblongata Present
TS28: piriform cortex Present
TS28: pons Present
TS28: thalamus Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory