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Gene Expression Data
Assay Details
Assay
Reference: J:125029 Pelosi M, et al., ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Mol Cell Biol. 2007 Sep;27(17):6163-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5694444
Gene symbol: Des
Gene name: desmin
Antibody: anti-desmin
Results
Specimen E13.5 +/-: embryonic day 13.5; Rock2tm1Sna/Rock2+ (more )
Note: section through forearm
Structure Level Pattern Image Note
TS21: forelimb musculature Present 7_E13.5 Desmin +/-

Specimen E13.5 -/-: embryonic day 13.5; Rock2tm1Sna/Rock2tm1Sna (more )
Note: section through forearm
Structure Level Pattern Image Note
TS21: forelimb musculature Present 7_E13.5 Desmin -/- The numbers of expressing cells are reduced in the mutant compared to controls, despite the apparently normal development of the extensor and flexor muscle groups.

Specimen E15.5 +/-: embryonic day 15.5; Rock2tm1Sna/Rock2+ (more )
Note: section through forearm
Structure Level Pattern Image Note
TS23: forearm muscle Present 7_E15.5 Desmin +/-

Specimen E15.5 -/-: embryonic day 15.5; Rock2tm1Sna/Rock2tm1Sna (more )
Note: section through forearm
Structure Level Pattern Image Note
TS23: forearm muscle Present 7_E15.5 Desmin -/- The numbers of expressing cells are reduced in the mutant compared to controls, despite the apparently normal development of the extensor and flexor muscle groups.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory