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Gene Expression Data
Assay Details
Assay
Reference: J:119296 Arnold SJ, et al., Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol. 2006 Aug 1;296(1):104-18
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5694432
Gene symbol: Smad9
Gene name: SMAD family member 9
Reporter: lacZ
Direct Detection
Results
Specimen 4A: embryonic day 5.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS8: extraembryonic visceral endoderm Present 4A
TS8: embryo endoderm Absent 4A
TS8: epiblast Absent 4A
Specimen 4B: embryonic day 7.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS11: extraembryonic visceral endoderm Present 4B
TS11: definitive endoderm Absent 4B
TS11: embryo mesoderm Absent 4B
TS11: neural ectoderm Absent 4B
Specimen 4B': embryonic day 7.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS11: extraembryonic visceral endoderm Present 4B'
TS11: definitive endoderm Absent 4B'
TS11: embryo mesoderm Absent 4B'
TS11: neural ectoderm Absent 4B'
Specimen 4C: embryonic day 8.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS13: trunk mesenchyme Present Regionally restricted 4C Expression is in the mesenchyme surrounding the forming heart.
TS13: heart Present 4C
TS13: embryo Weak Regionally restricted 4C Expression is in the tail bud region.
TS13: allantois Weak 4C
Specimen 4D: embryonic day 9.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Strong Regionally restricted 4D Expression is in the myocardial layer of the outflow and inflow tract.
TS15: outflow tract Strong Regionally restricted 4D Expression is in the myocardial layer.
TS15: endocardial lining Absent 4D
TS15: primitive ventricle Absent 4D
Specimen 4D': embryonic day 9.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Strong Regionally restricted 4D' Expression is in the myocardial layer of the outflow and inflow tract.
TS15: outflow tract Strong Regionally restricted 4D' Expression is in the myocardial layer.
TS15: endocardial lining Absent 4D'
TS15: primitive ventricle Absent 4D'
Specimen 4D'': embryonic day 9.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Strong Regionally restricted 4D'' Expression is in the myocardial layer of the outflow and inflow tract.
TS15: outflow tract Strong Regionally restricted 4D'' Expression is in the myocardial layer.
TS15: endocardial lining Absent 4D''
TS15: primitive ventricle Absent 4D''
Specimen 4E: embryonic day 10.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS17: optic cup inner layer Present Regionally restricted 4E Expression is in the rostral dorsal half.
TS17: eye surface ectoderm Absent 4E
Specimen 4E': embryonic day 10.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS17: optic cup inner layer Present Regionally restricted 4E' Expression is in the rostral dorsal half.
TS17: eye surface ectoderm Absent 4E'
Specimen 4F: embryonic day 10.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS17: sclerotome Present 4F
Specimen 4G: embryonic day 11.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS19: axial skeleton Present Regionally restricted 4G Expression is in the areas of chondrogenesis.
TS19: trunk mesenchyme Present Regionally restricted 4G Expression is in the ventral mesenchyme of the thoracic and abdominal regions.
TS19: hindbrain Weak 4G
TS19: neural retinal epithelium Weak 4G
Specimen 5A: embryonic day 14.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS22: intestine epithelium Strong 5A
TS22: intestine smooth muscle Strong 5A
TS22: choroid plexus Present 5A
TS22: gut Present 5A
TS22: vertebral cartilage condensation Present 5A
TS22: heart mesenchyme Present Regionally restricted 5A Expression is in a band of mesenchyme located in the atrioventricular region of the developing heart.
Specimen 5B: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS24: basal columns Present Regionally restricted 5B Expression is in a subset of motorneurons in the anterior spinal cord.
TS24: lens Present 5B
TS24: trigeminal ganglion Present 5B
TS24: cranium Present Regionally restricted 5B Expression is in cartilage.
Specimen 5C: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Structure Level Pattern Image Note
TS24: intestine epithelium Strong 5C
TS24: intestine smooth muscle Strong 5C
TS24: cartilage Present 5C
TS24: choroid plexus Present 5C
TS24: rib cartilage Present 5C
TS24: vertebral cartilage condensation Present 5C
TS24: basioccipital bone Present Regionally restricted 5C Expression is in cartilage.
TS24: mandible Present Regionally restricted 5C Expression is in cartilage.
TS24: maxilla Present Regionally restricted 5C Expression is in cartilage.
Specimen 5D: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: heart mesenchyme Present Regionally restricted 5D Expression is in the tissue separating the atria from the ventricles.
Specimen 5E: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: heart mesenchyme Present Regionally restricted 5E Expression is in the tissue separating the atria from the ventricles.
Specimen 5F: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: choroid plexus Present 5F
Specimen 5G: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: Bowman's capsule of maturing renal corpuscle Present Regionally restricted 5G Expression is in the epithelium.
TS24: collecting duct Present Regionally restricted 5G Expression is in the epithelium.
TS24: cortical early proximal tubule Present Regionally restricted 5G Expression is in the epithelium.
TS24: renal cortex Present Regionally restricted 5G Expression is in the juxtaglomerular apparatus.
Specimen 5H: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: intestine epithelium Strong Regionally restricted 5H Expression is in the epithelium layer of the villi.
TS24: intestine smooth muscle Strong Regionally restricted 5H Expression is in the outer smooth muscle layer.
Specimen 5I: embryonic day 16.5; Smad9tm1Rob/Smad9+ (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS24: bronchiole epithelium Present 5I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory