Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il1r1tm1.1Rbl
Name:	interleukin 1 receptor, type I; targeted mutation 1.1, Randy D Blakely
MGI ID:	MGI:5694158
Synonyms:	IL1RloxP
Gene:	Il1r1  Location: Chr1:40264240-40356417 bp, + strand  Genetic Position: Chr1, 18.81 cM
Alliance:	Il1r1tm1.1Rbl page

Germline Transmission:	Earliest citation of germline transmission: J:241345
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector to insert a loxP site upstream of exon 3, containing the translation initiation sequence, and a second loxP site downstream of exon 4 of the interleukin 1 receptor, type I (Il1r1) gene. An FRT-flanked neomycin resistance (neo) cassette was placed downstream of the 3' loxP site. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:241345)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il1r1 Mutation:	39 strains or lines available

Original:	J:241345 Robson MJ, et al., Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1. PLoS One. 2016;11(3):e0150068
All:	17 reference(s)