Six3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:116113 Geng X, et al., Expression of Six3 Opposite Strand (Six3OS) during mouse embryonic development. Gene Expr Patterns. 2007 Jan 2;7(3):252-257
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5693570
Gene symbol:	Six3
Gene name:	sine oculis-related homeobox 3

Antibody:	anti-Six3
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

3I ©

Specimen 3I: embryonic day 12.5 (more

)
Note: Double labeled: brown - Six3; blue - Six3os1 (assay MGI:5693535).

Structure	Level	Pattern	Image	Note
TS20: hypothalamus mantle layer	Present		3I
TS20: hypothalamus ventricular layer	Present		3I

4G ©

Specimen 4G: embryonic day 14.5; Six3^tm2Gco/Six3⁺, Tg(Pax6-cre,GFP)2Pgr/0 (more

)
Note: Conditional mutant. Double labeled: brown - Six3; blue - Six3os1 (assay MGI:5693535). These mice are indistinguishable from wild type.

Structure	Level	Pattern	Image	Note
TS22: retina	Present	Widespread	4G
TS22: lens	Present		4G

4H ©

Specimen 4H: embryonic day 14.5; Six3^tm2Gco/Six3^tm2.1Gco, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant. Double labeled: brown - Six3; blue - Six3os1 (assay MGI:5693535).

Structure	Level	Pattern	Image	Note
TS22: retina	Present	Regionally restricted	4H	Although expression persisted in the central portion of the retina, few, if any cells, could be detected in the distal retina.
TS22: lens	Present		4H

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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