Gene Expression Data
Assay Details
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Assay
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Reference:
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J:117178
Schmidl M, et al., Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo. J Biol Chem. 2006 Oct 20;281(42):31790-800
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5691800
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Gene symbol:
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Twsg1
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Gene name:
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twisted gastrulation BMP signaling modulator 1
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Probe:
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Tsg cDNA2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3A:
embryonic day 17.5
(more  )
Specimen
3A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: long bone |
Present |
Regionally restricted |
3A
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Expression is in the hypertrophic zone of the growth plates and is weak in the proliferating and resting cartilage and is absent in the proliferating zone of the epiphysis.
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Specimen
3C:
embryonic day 17.5
(more )
Specimen
3C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: humerus |
Present |
Regionally restricted |
3C
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Expression is in the hypertrophic zone of the growth plates and is weak in the proliferating and resting cartilage.
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| TS25: radius |
Present |
Regionally restricted |
3C
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Expression is in the hypertrophic zone of the growth plates and is weak in the proliferating and resting cartilage.
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Specimen
3E:
embryonic day 17.5
(more )
Specimen
3E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: digit mesenchyme |
Strong |
Regionally restricted |
3E
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Expression is in growth cartilage.
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Specimen
3F:
embryonic day 17.5
(more )
Specimen
3F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: ulna |
Present |
Regionally restricted |
3F
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Expression is in the hypertrophic zone of the growth plates and is weak in the proliferating and resting cartilage.
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| TS25: metacarpus |
Present |
Regionally restricted |
3F
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Expression is on the surface zone of a metacarpal joint.
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Specimen
3G:
embryonic day 17.5
(more )
Specimen
3G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3H:
postnatal day 30
(more )
Specimen
3H:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 30
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3I:
embryonic day 15.5
(more )
Specimen
3I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: humerus |
Strong |
Regionally restricted |
3I
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Expression is in the hypertrophic zone.
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Specimen
3J:
embryonic day 15.5
(more )
Specimen
3J:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: rib |
Present |
Regionally restricted |
3J
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Expression is in the hypertrophic zone.
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Specimen
3K:
embryonic day 15.5
(more )
Specimen
3K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3L:
embryonic day 15.5
(more )
Specimen
3L:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: vertebra |
Present |
Regionally restricted |
3L
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Expression is in cartilage.
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Specimen
4F:
postnatal newborn
(more )
Specimen
4F:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: radius |
Present |
Regionally restricted |
4F
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Expression is in the hypertrophic zone and is weak in the resting zone.
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Specimen
not shown 17.5:
embryonic day 17.5
(more )
Specimen
not shown 17.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: scapula |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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| TS25: tibia |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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Specimen
not shown newborn:
postnatal newborn
(more )
Specimen
not shown newborn:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: humerus |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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| TS27: radius |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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| TS27: scapula |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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| TS27: tibia |
Present |
Regionally restricted |
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Expression is in the hypertrophic cartilage zone.
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