About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:79480 Natarajan D, et al., Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development. 2002 Nov;129(22):5151-60
Assay type: RNA in situ
MGI Accession ID: MGI:5690101
Gene symbol: Gdnf
Gene name: glial cell line derived neurotrophic factor
Probe: Gdnf cDNA8
Probe preparation: Antisense RNA
Results
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS14: branchial pouch Present
TS14: mesenchyme derived from splanchnopleure Strong Regionally restricted Expression was at high levels in the splanchnic mesenchyme of the foregut (particularly the stomach).
Specimen 2A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: branchial pouch Present 2A
TS14: mesenchyme derived from splanchnopleure Strong Regionally restricted 2A Expression was at high levels in the splanchnic mesenchyme of the foregut (particularly the stomach).
Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial pouch Present 2B
TS15: mesenchyme derived from splanchnopleure Strong Regionally restricted 2B Expression was at high levels in the splanchnic mesenchyme of the foregut (particularly the stomach).
Specimen 2D: embryonic day 9.5; Rettm1Cos/Rettm1Cos (more )
Structure Level Pattern Image Note
TS15: foregut Present 2D Expression was normal in the mutant.
Specimen 2E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: mesenchyme derived from splanchnopleure Strong Regionally restricted 2E Expression was at high levels in the splanchnic mesenchyme of the foregut (particularly the stomach).
Specimen 2F: embryonic day 10.5-11.0 (more )
Structure Level Pattern Image Note
TS18: stomach Present 2F Expression in the stomach was reduced compared to E9.5.
TS18: small intestine Weak 2F
TS18: hindgut Strong Regionally restricted 2F High expression was evident in the prospective caecum.
Specimen 2H: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: hindgut Present Widespread 2H The posterior boundary of the ceacal expression domain extended caudally to cover the entire length of the hindgut.
TS21: intestine Weak Widespread 2H Lower but easily detectable expression was detected throughout the pre-ceacal gastrointestinal tract.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory