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Tg(Aplnr-cre/ERT2)#Krh
Transgene Detail
Summary
Symbol: Tg(Aplnr-cre/ERT2)#Krh
Name: transgene insertion, Kristy Red-Horse
MGI ID: MGI:5689869
Synonyms: ApjCreER, Apj-CreER
Transgene: Tg(Aplnr-cre/ERT2)#Krh  Location: unknown  
Alliance: Tg(Aplnr-cre/ERT2)#Krh page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Aplnr-cre/ERT2)#Krh expression driven by 1 gene
 
Mutation detailsThe transgene contains BAC RP24-301A16 into which an inducible cre recombinase gene (cre/ERT2) was introduced at the start site to achieve expression in the sinus venosus. Two lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:217615)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aplnr (mouse)
Summary of all recombinase alleles driven by Aplnr.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Transgene expression is not detected in the endocardium or epicardium.
References
Original:  J:217615 Chen HI, et al., VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory