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Gene Expression Data
Assay Details
Assay
Reference: J:70423 Eggenschwiler JT, et al., Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature. 2001 Jul 12;412(6843):194-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5689848
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Results
Specimen 3 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3_Nkx2.2 WT Expression is in V3 interneuron progenitors in a ventral domain.

Specimen 3 Shh: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: neural tube Absent 3_Nkx2.2 Shh

Specimen 3 opb2: embryonic day 10.5; Rab23opb2/Rab23opb2 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3_Nkx2.2 opb2 Expression is in a ventral and lateral domain and excluded in the dorsal third of the neural tube.

Specimen 3 Shh opb2: embryonic day 10.5; Rab23opb2/Rab23opb2, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3_Nkx2.2 Shh opb2 Expression is in a ventral and lateral domain and excluded in the dorsal third of the neural tube.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory