Tg(HLA-A*1101/H2-Kb)#Sette
Transgene Detail
|
|
| Symbol: |
Tg(HLA-A*1101/H2-Kb)#Sette |
| Name: |
transgene insertion, Alessandro Sette |
| MGI ID: |
MGI:3851009 |
| Synonyms: |
HLA-A11, HLA-A11/Kb |
| Transgene: |
Tg(HLA-A*1101/H2-Kb)#Sette Location: unknown
|
| Alliance: |
Tg(HLA-A*1101/H2-Kb)#Sette page
|
|
| Strain of Origin: |
BALB/c or C57BL/6
|
|
| Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The model was created by microinjecting a chimeric transgene combining a fragment of the genomic clone of the human HLA-A*1101 gene that included leader sequence, alpha1 and alpha2 domains ligated to a fragment of the murine H2-Kb gene containing the alpha3, transmembrane and cytoplasmic domains.
(J:150565)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:150565 Alexander J, et al., Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes. J Immunol. 1997 Nov 15;159(10):4753-61 |
| All: |
6 reference(s) |
|