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Gene Expression Data
Assay Details
Assay
Reference: J:163834 Paudyal A, et al., The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5689150
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Antibody: Anti-Vangl2 (N-13) sc-46561
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 12J: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: neural ectoderm Present Regionally restricted 12J Expression was predominantly in the neuroepithelial cell plasma membrane with an enrichment along apical membranes.

Specimen 12K: embryonic day 8.0; Ptk7chz/Ptk7chz (more )
Structure Level Pattern Image Note
TS12: neural ectoderm Present Regionally restricted 12K Some mutant embryos demonstrated a decrease in expression localization at the apical membranes, but it was not always reproducible and other embryos appeared to have normal expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory