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Gene Expression Data
Assay Details
Assay
Reference: J:163834 Paudyal A, et al., The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5689014
Gene symbol: Ptk7
Gene name: PTK7 protein tyrosine kinase 7
Antibody: Anti-Ptk7
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 11D,E: embryonic day 8.5 (more )
Note: 4 somite stage. Section was at the level around the site of neural tube closure 1.
Structure Level Pattern Image Note
TS12: future hindbrain Present 11E , 11D Expression was detected within the cell membranes.
TS12: mesenchyme derived from head mesoderm Present 11E , 11D Expression was detected within the cell membranes.

Specimen 11F,G: embryonic day 8.5; Ptk7chz/Ptk7chz (more )
Note: 4 somite stage. Section was at the level around the site of neural tube closure 1.
Structure Level Pattern Image Note
TS12: future hindbrain Weak 11G , 11F Expression was significantly reduced in cell membranes of the mutant.
TS12: mesenchyme derived from head mesoderm Weak 11G , 11F Expression was significantly reduced in cell membranes of the mutant.

Specimen 12E: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: mesenchyme derived from head mesoderm Present Regionally restricted 12E Expression was detected within the cell membranes.
TS12: neural ectoderm Present Regionally restricted 12E Expression was detected within the cell membranes.

Specimen 12F: embryonic day 8.0; Celsr1Crsh/Celsr1Crsh (more )
Structure Level Pattern Image Note
TS12: mesenchyme derived from head mesoderm Present Regionally restricted 12F Expression was detected within the cell membranes in the mutant with no obvious defect in localization.
TS12: neural ectoderm Present Regionally restricted 12F Expression was detected within the cell membranes in the mutant with no obvious defect in localization.

Specimen 12G: embryonic day 8.0; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS12: mesenchyme derived from head mesoderm Present Regionally restricted 12G Expression was detected within the cell membranes in the mutant with no obvious defect in localization.
TS12: neural ectoderm Present Regionally restricted 12G Expression was detected within the cell membranes in the mutant with no obvious defect in localization.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory