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Fzd9tm1.1Nat
Targeted Allele Detail
Summary
Symbol: Fzd9tm1.1Nat
Name: frizzled class receptor 9; targeted mutation 1.1, Jeremy Nathans
MGI ID: MGI:5688880
Synonyms: Fzd9-CKO-AP
Gene: Fzd9  Location: Chr5:135277792-135279901 bp, - strand  Genetic Position: Chr5, 75.08 cM
Alliance: Fzd9tm1.1Nat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change, Reporter)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted (1) within the first coding exon 5' of the initiator methionine codon, and (2) 3' of an SV40 polyadenylation signal that was inserted immediately 3' of the 3' UTR. The following DNA segments were added immediately downstream of the 3' loxP site: (1) the coding region for human placental alkaline phosphatase (AP), and (2) a phosphoglycerate kinase (PGK)-Neo cassette flanked by FRT sites (FNF). Flp-mediated recombination removed the FRT-flanked neo cassette. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fzd9 Mutation:  36 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory