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Gene Expression Data
Assay Details
Assay
Reference: J:108225 Knight AS, et al., Developmental expression analysis of the mouse and chick orthologues of IRF6: The gene mutated in Van der Woude syndrome. Dev Dyn. 2006 May;235(5):1441-7
Assay type: RNA in situ
MGI Accession ID: MGI:5688618
Gene symbol: Irf6
Gene name: interferon regulatory factor 6
Probe: Irf6 cDNA2
Probe preparation: Antisense labelled with P33 RNA
Results
Specimen 1I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch maxillary component ectoderm Present 1I

Specimen 1J: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: latero-nasal process ectoderm Present 1J Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.
TS18: medial-nasal process ectoderm Present 1J Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.

Specimen 1K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxilla primordium Present Regionally restricted 1K Expression is present in the epithelium of the intermaxillary segment.
TS19: naso-lacrimal groove Strong 1K
TS19: surface ectoderm Strong Regionally restricted 1K Expression is present in the ectoderm surrounding the developing eyes.
TS19: medial-nasal process ectoderm Present 1K

Specimen 1L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: naris Present 1L
TS21: vibrissa follicle Present 1L

Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Present Regionally restricted 2D Expression is present in the tip of the palatal shelf extending along the presumptive nasal palatal epithelium but is absent from the presumptive oral palatal epithelium.
TS21: enamel knot Present 2D Expression is strongest in the enamel knot and enamel organ close to the cervical loop.
TS21: enamel organ Present 2D Expression is strongest in the enamel knot and enamel organ close to the cervical loop.
TS21: upper jaw incisor epithelium Present 2D Expression is strongest in the enamel knot and enamel organ close to the cervical loop.
TS21: upper jaw molar epithelium Present 2D Expression is strongest in the enamel knot and enamel organ close to the cervical loop.

Specimen 2E: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 2E Expression is present in the medial edge during palatal fusion. It is also present in the epithelia at the junction of the primary and secondary palate.
TS22: nasal septum epithelium Present Regionally restricted 2E Expression is present in the epithelium along the base.

Specimen 2F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Strong Regionally restricted 2F Expression is present in the medial edge epithelial seam, as well as in the nasal and orgal palatal epithelia as the seam degenerates.
TS22: upper jaw incisor enamel organ Present 2F Expression is strongest in the enamel knot and enamel organ close to the cervical loop.
TS22: upper jaw molar enamel organ Present 2F Expression is strongest in the enamel knot and enamel organ close to the cervical loop.
TS22: enamel knot Present 2F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory