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Gene Expression Data
Assay Details
Assay
Reference: J:108225 Knight AS, et al., Developmental expression analysis of the mouse and chick orthologues of IRF6: The gene mutated in Van der Woude syndrome. Dev Dyn. 2006 May;235(5):1441-7
Assay type: RNA in situ
MGI Accession ID: MGI:5688617
Gene symbol: Irf6
Gene name: interferon regulatory factor 6
Probe: Irf6 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted 1A Expression is seen in the line of fusion between apposed mandibular processes.
TS17: latero-nasal process ectoderm Present Regionally restricted 1A Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.
TS17: medial-nasal process ectoderm Present Regionally restricted 1A Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present 1E Expression is seen in the line of fusion between apposed mandibular processes.
TS17: 1st branchial arch maxillary component ectoderm Present 1E
TS17: 2nd branchial arch ectoderm Present 1E

Specimen 1B: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present 1B
TS18: latero-nasal process ectoderm Strong Regionally restricted 1B Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.
TS18: medial-nasal process ectoderm Strong Regionally restricted 1B Expression is detected in the epithelial fusion zone between the medial and lateral nasal processes.

Specimen 1F: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present 1F
TS18: 1st branchial arch maxillary component ectoderm Present 1F

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxilla primordium Present Regionally restricted 1C Expression is present in the epithelium of the intermaxillary segment.

Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: naso-lacrimal groove Strong 1G

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: naris Present 1D
TS21: incisor Strong 1D
TS21: molar Strong 1D
TS21: oral epithelium Present Regionally restricted 1D Expression is present in the epithelium lining the floor of the mouth, particularly in the region close to the base of the tongue.

Specimen 1H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa follicle Present 1H
TS21: hair follicle Present 1H Expression is present in the supra- and infra-orbital hair follicles.

Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present Regionally restricted 2A Expression is present in the tips immediately prior to palatal shelf elevation.
TS21: upper jaw tooth Present 2A

Specimen 2B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Present Regionally restricted 2B Expression is present in the medial edge during palatal fusion.
TS22: upper jaw tooth Present 2B

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Present Regionally restricted 2C Expression is present in the medial edge during palatal fusion.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory