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Gene Expression Data
Assay Details
Assay
Reference: J:153562 Acampora D, et al., Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm. Mech Dev. 2009 Oct;126(10):882-97
Assay type: RNA in situ
MGI Accession ID: MGI:5688177
Gene symbol: Pax6
Gene name: paired box 6
Results
Specimen S4C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present S4C
Specimen S4G: embryonic day 9.5; Otx2tm9Asim/Otx2tm9Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present S4G In mutants with less severe head defects, expression was retained, although abnormal. In mutants with a headless phenotype, expression was abolished.
Specimen 5D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present 5D
Specimen 5I: embryonic day 9.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present 5I Stable expression, although heavily abnormal, was maintained in the mutant.
Specimen 5N: embryonic day 9.5; Otx2tm10Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Present 5N Stable expression, although heavily abnormal, was maintained in the mutant.
Specimen 5S: embryonic day 9.5; Otx2tm11Asim/Otx2tm11Asim (more )
Structure Level Pattern Image Note
TS15: future brain Absent 5S
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory