Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Col10a1tm3.1(cre/ERT)Ksec
Name:	collagen, type X, alpha 1; targeted mutation 3.1, Kathryn S E Cheah
MGI ID:	MGI:5662425
Synonyms:	Col10a1-CreERt
Gene:	Col10a1  Location: Chr10:34265977-34273081 bp, + strand  Genetic Position: Chr10, 18.85 cM, cytoband B1-B3
Alliance:	Col10a1tm3.1(cre/ERT)Ksec page

Germline Transmission:	Earliest citation of germline transmission: J:213921
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Col10a1tm3.1(cre/ERT)Ksec expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Col10a1 (MGI:88445)   Mutation details: A tamoxifen-inducible cre recombinase fusion gene (cre/ERt) and an FRT-flanked neomycin resistance cassette were inserted at the translation initiation site in exon 2. Flp-mediated recombination removed the selection cassette. (J:213921)

Activity:	Tissue activity of this recombinase allele
Driver:	Col10a1 (mouse) Summary of all recombinase alleles driven by Col10a1. Comparative matrix view of recombinase activities Alliance mouse Col10a1 gene page

In Mice Carrying this Mutation:

6 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col10a1 Mutation:	27 strains or lines available

Original:	J:213921 Yang L, et al., Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12097-102
All:	2 reference(s)