Chrna7tm2.1(cre)Swr
Targeted Allele Detail
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Symbol: |
Chrna7tm2.1(cre)Swr |
Name: |
cholinergic receptor, nicotinic, alpha polypeptide 7; targeted mutation 2.1, Scott W Rogers |
MGI ID: |
MGI:5662228 |
Synonyms: |
Chrna7-IRES-Cre |
Gene: |
Chrna7 Location: Chr7:62748440-62862274 bp, - strand Genetic Position: Chr7, 34.47 cM
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Alliance: |
Chrna7tm2.1(cre)Swr page
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Allele Type: |
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Targeted (Recombinase) |
Mutations: |
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Insertion, Intragenic deletion
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Chrna7tm2.1(cre)Swr expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Chrna7 (MGI:99779) |
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Mutation details: The stop codon was replaced with a hemagglutinin (HA) epitope tag (YPYDVPDY), IRES, cre recombinase gene and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette.
(J:223063)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Chrna7
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Chrna7 Mutation: |
49 strains or lines available
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Original: |
J:223063 Rogers SW, et al., Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. Am J Med Genet A. 2012 May;158A(5):1135-44 |
All: |
4 reference(s) |
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