Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | Notes | References

Symbol:	Dcpp1tm1.1(cre/ERT2)Ovi
Name:	demilune cell and parotid protein 1; targeted mutation 1.1, Catherine E Ovitt
MGI ID:	MGI:5661581
Synonyms:	Dcpp1GCE, Dcpp1-GCE, Dcpp1-GFPCreErT2, Dcpp1tm1(cre/ERT2)Ovi, Dcpp1tm1(GCE)Ovi
Gene:	Dcpp1  Location: Chr17:24099850-24101827 bp, + strand  Genetic Position: Chr17, 12.11 cM
Alliance:	Dcpp1tm1.1(cre/ERT2)Ovi page

Germline Transmission:	Earliest citation of germline transmission: J:229520
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Dcpp1tm1.1(cre/ERT2)Ovi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Dcpp1 (MGI:105949)   Mutation details: The EGFP-cre/ERT2 (GCE) fragment with an SV40 poly adenylation site and neomycin resistance cassette were inserted immediately downstream of the translational initiation codon ATG. The knock-in construct interrupted coding sequence in exon 2 and placed the GCE gene under the control of the endogenouse regulatory sequences. Flp-mediated recombination removed the selection cassette. No expression of GFP was detected with fluorescence or using antibody to GFP. The fusion cre is expressed in intercalated duct cells of parotid gland and serous cells of sublingual gland. (J:229520)

Activity:	Tissue activity of this recombinase allele
Driver:	Dcpp1 (mouse) Summary of all recombinase alleles driven by Dcpp1. Comparative matrix view of recombinase activities Alliance mouse Dcpp1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dcpp1 Mutation:	5 strains or lines available

Original:	J:229520 Maruyama EO, et al., Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands. PLoS One. 2016;11(1):e0146711
All:	2 reference(s)