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Gene Expression Data
Assay Details
Assay
Reference: J:96501 Sasaki T, et al., LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 1;278(1):130-43
Assay type: RNA in situ
MGI Accession ID: MGI:5661447
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Probe: Lef1 cDNA7
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: jaw primordium mesenchyme Present Regionally restricted 1A/B Expressed in the dental lamina and the cranial neural crest-derived mesenchyme.
TS20: oral epithelium Absent 1A/B

Specimen 1C/D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present Regionally restricted 1C/D Expressed in the bud stage dental epithelium.
TS21: tooth mesenchyme Present Regionally restricted 1C/D Expressed in the cranial neural crest-derived mesenchyme.

Specimen 1E/F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Present 1E/F
TS22: inner enamel epithelium Present 1E/F
TS22: outer enamel epithelium Present 1E/F
TS22: tooth mesenchyme Present Regionally restricted 1E/F Expressed in the cranial neural crest-derived mesenchyme.

Specimen 1G/H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: inner enamel epithelium Present 1G/H
TS24: dental papilla Present 1G/H

Specimen 1I/J: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present Regionally restricted 1I/J
TS26: dental papilla Present Regionally restricted 1I/J Expressed in the preodontoblast cells.
TS26: cervical loop Present 1I/J


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory