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Gene Expression Data
Assay Details
Assay
Reference: J:123846 Morimoto M, et al., The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development. 2007 Apr;134(8):1561-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660854
Gene symbol: Notch1
Gene name: notch 1
Antibody: Anti-Notch1
Assay notes: This antibody recognizes the active form of the protein.
Results
Specimen 6G: embryonic day 10.5 (more )
Note: Double labeled: magenta - Notch1; green - Mesp2 (assay MGI:5660853).
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 6G right , 6G middle Expression is in the anterior presomitic mesoderm.
Specimen 6H: embryonic day 10.5; Ripply2tm1.1Ysa/Ripply2tm1.1Ysa (more )
Note: Double labeled: magenta - Notch1; green - Mesp2 (assay MGI:5660853).
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 6H middle , 6H right Notch1 activity in the anterior presomitic mesoderm is repressed in this mutant, activity in the posterior presomitic mesoderm is normal.
Specimen 6I: embryonic day 10.5; Ripply2tm1.1Ysa/Ripply2tm1.1Ysa (more )
Note: Double labeled: magenta - Notch1; green - Mesp2 (assay MGI:5660853).
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 6I right , 6I middle Notch1 activity in the anterior presomitic mesoderm is repressed in this mutant, activity in the posterior presomitic mesoderm is normal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory