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Gene Expression Data
Assay Details
Assay
Reference: J:149253 Kulkarni RM, et al., NFATc1 regulates lymphatic endothelial development. Mech Dev. 2009 May-Jun;126(5-6):350-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660608
Gene symbol: Pdpn
Gene name: podoplanin
Antibody: Anti-Podoplanin (clone 8.1.1)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 1E: embryonic day 12.5 (more )
Note: Triple labeled: red - Pdpn; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted 1E Expressed in jugular lymph sacs endothelial cells. Coexpressed with Prox1 and Nfatc1.
TS20: cardinal vein Absent 1E Not expressed in endothelial cells.
Specimen S1D: embryonic day 12.5 (more )
Note: Triple labeled: red - Pdpn; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS20: lymphatic system Present Regionally restricted S1D Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen S1F: embryonic day 14.5 (more )
Note: Triple labeled: red - Pdpn; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1F Expressed in the dermal lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen S1H: embryonic day 14.5 (more )
Note: Triple labeled: red - Pdpn; green - Nfatc1 (assay MGI:5660396); blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted S1H Expressed in the pulmonary lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen S2A: embryonic day 11.5 (more )
Note: Double labeled: red - Pdpn; blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS19: lymphatic system Present Regionally restricted S2A Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Prox1.
Specimen S2B: embryonic day 11.5; Nfatc1tm1Glm/Nfatc1tm1Glm (more )
Note: Double labeled: red - Pdpn; blue - Prox1 (assay MGI:5660552).
Structure Level Pattern Image Note
TS19: lymphatic system Present Regionally restricted S2B Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Prox1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
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