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Gene Expression Data
Assay Details
Assay
Reference: J:35026 Schmid P, et al., Dynamic expression pattern of the myc protooncogene in midgestation mouse embryos. Science. 1989 Jan 13;243(4888):226-9
Assay type: RNA in situ
MGI Accession ID: MGI:5660327
Gene symbol: Myc
Gene name: myelocytomatosis oncogene
Probe: SVmyc1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probe was reduced to 100-200 bases by partial hydrolysis.
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Strong 1A Discontinuous expression, absent in hematopoietic foci.
TS20: gut Moderate 1A
TS20: lung Moderate 1A
TS20: pancreas Moderate 1A
TS20: metanephros Present 1A
TS20: vertebral pre-cartilage condensation Present Regionally restricted 1A Expression is in the cerebral vertebra.
TS20: spinal ganglion Present Regionally restricted 1A Expression is in the ganglia of the thoracic spinal cord.
TS20: somite Present Regionally restricted 1A Expression is in somites 49-51.
TS20: heart Absent 1A
TS20: skeletal muscle Absent 1A

Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gut epithelium Strong 1C
TS22: thymus primordium Strong 1C
TS22: gut Strong Regionally restricted 1C Strong in the epithelium, absent in the mesodermal layers of the gut.
TS22: pancreas epithelium Present Regionally restricted 1C Expression is in the branching tubules.
TS22: intervertebral disc Present 1C
TS22: lower jaw molar enamel organ Present 1C
TS22: lung mesenchyme Present 1C
TS22: metanephros Present 1C
TS22: upper jaw molar enamel organ Present 1C
TS22: liver Present 1C Expression is in hepatocytes and is weak in megakaryocytes.
TS22: tongue Moderate Non-Uniform 1C
TS22: heart Absent 1C
TS22: maturing glomerular tuft Absent 1C
TS22: skeletal muscle Absent 1C

Specimen 1D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intervertebral disc Strong 1D
TS24: lower jaw molar enamel organ Strong 1D
TS24: nasal cavity epithelium Strong 1D
TS24: submandibular gland Strong 1D
TS24: thymus Strong 1D
TS24: upper jaw molar enamel organ Strong 1D
TS24: intestine Present 1D
TS24: metanephros Present 1D
TS24: pancreatic acinus Present 1D
TS24: pancreatic duct Present 1D
TS24: rib cartilage Present 1D
TS24: trachea cartilaginous ring Present 1D
TS24: renal tubule Present Regionally restricted 1D Expression is in the epithelia of the collecting tubules.
TS24: sternum Present Regionally restricted 1D Expression is in the cartilage.
TS24: heart Absent 1D
TS24: skeletal muscle Absent 1D

Specimen 2A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS28: placenta Present Regionally restricted 2A/B Absent in the maternal part of the placenta.
TS17: labyrinthine zone Present 2A/B

Specimen 2C/D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gut epithelium Strong 2C/D
TS22: gut Strong Regionally restricted 2C/D Strong in the epithelium, absent in the mesodermal layers of the gut.

Specimen 2E/F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: gut epithelium Strong Graded 2E/F Strongest expression is in the proliferating cells in the crypts.

Specimen Table 1 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: extraembryonic component Strong
TS20: liver Strong
TS20: lung Strong
TS20: metanephros Strong

Specimen Table 1 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gut epithelium Strong
TS22: pancreas Strong
TS22: thymus primordium Strong
TS22: liver Present
TS22: lung Present
TS22: metanephros Present

Specimen Table 1 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland Strong
TS24: thymus Strong
TS24: gut epithelium Present
TS24: metanephros Present
TS24: pancreas Present
TS24: liver Weak
TS24: lung Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory