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Nppctm1.1Ajho
Targeted Allele Detail
Summary
Symbol: Nppctm1.1Ajho
Name: natriuretic peptide type C; targeted mutation 1.1, Adrian J Hobbs
MGI ID: MGI:5660304
Synonyms: Nppcfl, Nppcflox
Gene: Nppc  Location: Chr1:86594015-86598295 bp, - strand  Genetic Position: Chr1, 43.98 cM
Alliance: Nppctm1.1Ajho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215744
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:215744)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nppc Mutation:  8 strains or lines available
References
Original:  J:215744 Moyes AJ, et al., Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest. 2014 Sep 2;124(9):4039-51
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory