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Gene Expression Data
Assay Details
Assay
Reference: J:220985 Huckert M, et al., Mutations in the latent TGF-beta binding protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfecta. Hum Mol Genet. 2015 Jun 1;24(11):3038-49
Assay type: RNA in situ
MGI Accession ID: MGI:5660115
Gene symbol: Ltbp3
Gene name: latent transforming growth factor beta binding protein 3
Probe: T36602
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 14.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS22: vertebral cartilage condensation Present 3A
TS22: spinal cord lateral wall Present 3A Expression in cells surrounding the lumen of the neural tube.
Specimen 3B: embryonic day 16.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS24: mandible Present 3B
Specimen 3C: embryonic day 16.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS24: cranium Present 3C Expression in base of the skull bones.
TS24: cochlea Present 3C
Specimen 3D: embryonic day 14.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS22: diencephalon ventricular layer Present 3D Expression in the ventricular and subventricular zones of the developing brain vesicles.
TS22: telencephalon ventricular layer Present 3D Expression in the ventricular and subventricular zones of the developing brain vesicles.
Specimen 3E: embryonic day 18.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: duodenum Present Regionally restricted 3E Expression is found at the base of the intestinal crypts of the small and large intestine.
Specimen 3F: embryonic day 14.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS22: lung Weak 3F
TS22: dorsal aorta Present 3F
TS22: pulmonary artery Present 3F
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: outflow tract Present
Specimen 3G: embryonic day 14.5 (more )
Note: frontal section; cap stage tooth
Structure Level Pattern Image Note
TS22: lower jaw incisor Present 3G
Specimen 3H: embryonic day 14.5 (more )
Note: frontal section; cap stage tooth
Structure Level Pattern Image Note
TS22: molar Present 3H
Specimen 3I: embryonic day 16.5 (more )
Note: sagittal section; bell stage tooth
Structure Level Pattern Image Note
TS24: lower jaw incisor epithelium Present Non-Uniform 3I Expression is strongest in the most differentiated areas, such as the rostral part of the incisors.
TS24: lower jaw incisor mesenchyme Present Non-Uniform 3I Expression is strongest in the most differentiated areas, such as the rostral part of the incisors.
Specimen 3J: embryonic day 16.5 (more )
Note: sagittal section; bell stage tooth
Structure Level Pattern Image Note
TS24: molar epithelium Present Non-Uniform 3J Expression is strongest in the most differentiated areas, such as the molar cusp tips.
TS24: molar mesenchyme Present Non-Uniform 3J Expression is strongest in the most differentiated areas, such as the molar cusp tips.
Specimen 3K: embryonic day 18.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: lower jaw incisor Present Single cells 3K Expression present in differentiating ameloblasts and odontoblasts.
Specimen 3L: embryonic day 18.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: molar Present Single cells 3L Expression present in differentiating ameloblasts and odontoblasts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory