Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Epxtm1(EGFP/Cre/ERT2)Wtsi
Name:	eosinophil peroxidase; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:5660003
Synonyms:	Epxtm1(EGFP_CreERT2)Wtsi
Gene:	Epx  Location: Chr11:87754826-87766362 bp, - strand  Genetic Position: Chr11, 52.25 cM
Alliance:	Epxtm1(EGFP/Cre/ERT2)Wtsi page

Mutant Cell Line:	CEPD0045_1_B06
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	EUCOMMTOOLS

Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Epxtm1(EGFP/Cre/ERT2)Wtsi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Epx (MGI:107569)   Mutation details: According the the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exons 6 and 7, and inserted into the intron between exons 5 and 6 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette. (J:157065)

Activity:	Tissue activity of this recombinase allele
Driver:	Epx (mouse) Summary of all recombinase alleles driven by Epx. Alliance mouse Epx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Epx Mutation:	34 strains or lines available

Original:	J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:	2 reference(s)