Tg(SERPINA1-TNFRSF13B/FCGR3A)5508Siec
Transgene Detail
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| Symbol: |
Tg(SERPINA1-TNFRSF13B/FCGR3A)5508Siec |
| Name: |
transgene insertion 5508, Swiss Institute for Experimental Cancer Research |
| MGI ID: |
MGI:5649265 |
| Synonyms: |
h TACI:Fc, Tg(TNFRSF13B-FCGR3A)5508Siec |
| Transgene: |
Tg(SERPINA1-TNFRSF13B/FCGR3A)5508Siec Location: unknown
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| Alliance: |
Tg(SERPINA1-TNFRSF13B/FCGR3A)5508Siec page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(SERPINA1-TNFRSF13B/FCGR3A)5508Siec expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
FCGR3A (2214) |
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| human |
TNFRSF13B (23495) |
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This transgene expresses a fusion of two human genes, TNFRSF13B and FCGR3A. |
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Mutation details: A cassette encoding the signal peptide of human Ig G heavy chain, the extracellular domain of human TNFRSF13B (TACI, amino acids 2-118) and the Fc domain of human Ig G1 was expressed under the control of a human alpha1 antitrypsin promoter.
(J:73083)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:73083 Schneider P, et al., Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001 Dec 3;194(11):1691-7 |
| All: |
3 reference(s) |
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Analysis Tools
