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Gene Expression Data
Assay Details
Assay
Reference: J:50982 Urase K, et al., Detection of activated caspase-3 (CPP32) in the vertebrate nervous system during development by a cleavage site-directed antiserum. Brain Res Dev Brain Res. 1998 Nov 1;111(1):77-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5648839
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-p20/17
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody recognizes the cleavage site only after it was cleaved.
Results
Specimen 2F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 2F

Specimen 2I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Non-Uniform 2I The number of positive cells was not equal at different position along the anteroposterial axis.

Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trigeminal ganglion Present 3B

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present 3E The number of Positive cells increased and peaked at E14.5.

Specimen 3H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trigeminal ganglion Present Single cells 3H The number of expressing cells decreased. Only a few positive cells were detected.

Specimen 4B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Present 4B Many positive cells were detected.

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present 4D Many positive cells were detected.

Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present 4E Many positive cells were detected.

Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present 4F Many positive cells were detected.

Specimen 4I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present 4I

Specimen 4L: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cortical plate Weak Single cells 4L Very few positive cells were detected.

Specimen 4O: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent 4O


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory