Tg(IRBP-HEL)1Rc
Transgene Detail
|
|
| Symbol: |
Tg(IRBP-HEL)1Rc |
| Name: |
transgene insertion 1, Richard Cornall |
| MGI ID: |
MGI:5648245 |
| Synonyms: |
Lo-Moe (TrpHEL3), rHEL |
| Transgene: |
Tg(IRBP-HEL)1Rc Location: unknown
|
| Alliance: |
Tg(IRBP-HEL)1Rc page
|
|
| Strain of Origin: |
C57BL/6 or CBA/CaJ
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: These transgenic mice express hen egg lysozyme (HEL) in retinal photoreceptor cells. The expression construct comprised an extracellular lysozyme domain and transmembrane region derived from the MHC class I molecule H-2Kb under the control of the human IRBP promoter. Several lines were generated, and one transgenic line was selected for detailed analysis.
(J:145054)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
|
|
|
The transgene was microinjected into fertilized oocytes from a cross of CBA/CaJ and C57BL/6 mice.
|
| Original: |
J:145054 Lambe T, et al., Limited peripheral T cell anergy predisposes to retinal autoimmunity. J Immunol. 2007 Apr 1;178(7):4276-83 |
| All: |
5 reference(s) |
|
Analysis Tools
