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Tg(Krt14-Col18a1)J4Pih
Transgene Detail
Summary
Symbol: Tg(Krt14-Col18a1)J4Pih
Name: transgene insertion J4, Taina Pihlajaniemi
MGI ID: MGI:5645734
Transgene: Tg(Krt14-Col18a1)J4Pih  Location: unknown  
Alliance: Tg(Krt14-Col18a1)J4Pih page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Krt14-Col18a1)J4Pih expresses 1 gene
 
Mutation detailsA transgenic mouse cDNA construct encoding the signal sequence and C-terminal endostatin part of the type alpha1(XVIII) chain was expressed under the control of the human K14 promoter. Three transgenic founders, K18, G20, and J4, were obtained. Expression in line J4 was the strongest and was studied further. (J:95251)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:95251 Elamaa H, et al., Endostatin overexpression specifically in the lens and skin leads to cataract and ultrastructural alterations in basement membranes. Am J Pathol. 2005 Jan;166(1):221-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory