Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdgfratm1.1(EGFP/cre/ERT2)Hyma
Name:	platelet derived growth factor receptor, alpha polypeptide; targeted mutation 1.1, Hiroyuki Miwa
MGI ID:	MGI:5644346
Synonyms:	PDGFRalphaGCE
Gene:	Pdgfra  Location: Chr5:75312953-75358876 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance:	Pdgfratm1.1(EGFP/cre/ERT2)Hyma page

Germline Transmission:	Earliest citation of germline transmission: J:221424
Parent Cell Line:	KTPU8 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Pdgfratm1.1(EGFP/cre/ERT2)Hyma expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pdgfra (MGI:97530)   Mutation details: A fusion of EGFP and an inducible cre recombinase gene (EGFP/cre/ERT2) was inserted at the translation initiation site. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the fusion. (J:221424)

Activity:	Tissue activity of this recombinase allele
Driver:	Pdgfra (mouse) Summary of all recombinase alleles driven by Pdgfra. Comparative matrix view of recombinase activities Alliance mouse Pdgfra gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

15 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:	85 strains or lines available

Original:	J:221424 Miwa H, et al., Generation and characterization of PDGFRalpha-GFPCreER(t2) knock-In mouse line. Genesis. 2015 May;53(5):329-36
All:	5 reference(s)