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Gene Expression Data
Assay Details
Assay
Reference: J:37192 Huynh DP, et al., Expression of neurofibromatosis 2 transcript and gene product during mouse fetal development. Cell Growth Differ. 1996 Nov;7(11):1551-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5644255
Gene symbol: Nf2
Gene name: neurofibromin 2
Antibody: Antibody 5990
Results
Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: trophectoderm Strong 3A
TS28: decidua Strong 3A
TS14: embryo mesenchyme Present 3A
TS14: heart Present 3A
TS14: central nervous system Absent 3A
Specimen 3B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: intestine Weak 3B
TS18: lung Weak 3B
TS18: metanephros Weak 3B
TS18: tongue Weak 3B
TS18: liver Trace 3B
TS18: neural tube ventricular layer Absent 3B
Specimen 3C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: brain mantle layer Strong 3C
TS21: spinal cord mantle layer Strong 3C
TS21: intestine Weak 3C
TS21: lung Weak 3C
TS21: metanephros Weak 3C
TS21: tongue muscle Weak 3C
TS21: liver Trace 3C
TS21: spinal cord ventricular layer Absent 3C Expression is absent in the ependymal layer.
Specimen 3D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: brain mantle layer Present 3D
TS23: spinal cord mantle layer Present 3D
TS23: intestine Weak 3D
TS23: lung Weak 3D
TS23: metanephros Weak 3D
TS23: tongue muscle Weak 3D
TS23: liver Trace 3D
Specimen 5A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present 5A Expression is in postmitotic migrating neurons.
TS24: cortical plate Weak 5A Expression is in postmitotic neurons.
TS24: cerebral cortex ventricular layer Absent 5A Expression is absent in mitotic neuroblasts.
Specimen 5C: embryonic day 13.0 (more )
Note: (E) is a higher magnification of (C).
Structure Level Pattern Image Note
TS21: spinal cord mantle layer Strong 5E , 5C Expression is in the cytoplasm and perinuclear region of differentiated neurons and glial cells.
TS21: spinal cord marginal layer Strong 5E , 5C Expression is in the cytoplasm and perinuclear region of differentiated neurons and glial cells.
TS21: spinal cord ventricular layer Absent 5C , 5E Expression is in absent in the ependymal layer.
Specimen 6A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: trophectoderm Strong 6A
TS28: decidua Strong 6A
TS14: embryo mesenchyme Present 6A
TS14: heart Present 6A
TS14: central nervous system Absent 6A
Specimen 6C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: brain mantle layer Present 6C
TS18: head mesenchyme Present 6C
Specimen 6D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: heart Present Regionally restricted 6D Expression is in the endocardium, absent in the bulbar ridge.
TS18: endocardial lining Present 6D
Specimen 6E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: cornea epithelium Strong 6E
TS18: lens vesicle Strong 6E
TS18: pigmented retinal epithelium Strong 6E
Specimen 6F: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: epidermis Strong Single cells 6F Expression is in keratinocytes, absent in mesenchyme adjacent to the dermis.
TS23: cartilage Weak 6F
TS23: dermis Absent 6F
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present
TS28: lens Present
TS28: pigmented retinal epithelium Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory