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Gene Expression Data
Assay Details
Assay
Reference: J:190313 Moreno-Garcia MA, et al., The methylmalonic aciduria related genes, Mmaa, Mmab, and Mut, are broadly expressed in placental and embryonic tissues during mouse organogenesis. Mol Genet Metab. 2012 Nov;107(3):368-74
Assay type: RNA in situ
MGI Accession ID: MGI:5642219
Gene symbol: Mmab
Gene name: methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
Probe: Mmab cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B,E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: labyrinthine zone Present 1B
TS17: spongiotrophoblast Present 1E , 1B
TS17: trophoblast giant cell Present 1E , 1B
Specimen 2H-M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 2H Expression was ubiquitous in all structures along the anterior and posterior axis.
TS17: heart Present 2J , 2H
TS17: branchial arch Present 2H
TS17: central nervous system Present 2H , 2I
TS17: neural tube Present 2H , 2I
TS17: nephric duct Trace 2L , 2K , 2H
TS17: hindgut Weak 2M , 2H
Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: blood vessel endothelium Present 3B
TS19: head mesenchyme Present 3B
Specimen 3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 3E
Specimen 3H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart Present 3H
Specimen 3K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: liver Present 3K
Specimen 3N: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3N
TS19: blood vessel Present Regionally restricted 3N Expression was detected in intersomitic blood vessels.
Specimen 3Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung Present Regionally restricted 3Q Expression was detected in lung endoderm.
Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Present 4B
TS20: head mesenchyme Present 4B
Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 4E
Specimen 4H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Present 4H
Specimen 4K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Present 4K
TS20: lung vascular element Present 4K
TS20: lung Present Regionally restricted 4K Expression was in endothelial cells, lung buds and surrounding mesenchyme.
Specimen 4N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midgut mesenchyme Weak 4N
TS20: midgut Weak Regionally restricted 4N Low levels of expression were detected in the mesenchyme but not in the gut endoderm.
Specimen 4Q: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: urogenital sinus Strong 4Q
TS20: hindgut Strong Regionally restricted 4Q Expression was high in the rectum.
Specimen 4T: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Present Widespread 4T
Specimen 4W: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: metanephros Present 4W
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory