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Gene Expression Data
Assay Details
Assay
Reference: J:169107 Kunwar AJ, et al., Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5642070
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament (AB1981)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present Regionally restricted 3A Expression is in bundles of fibers.

Specimen 3B: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present Regionally restricted 3B Expression in some fiber bundles is missing in this mutant.

Specimen 3G: embryonic day 14.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3G Expression is to/from the thalamus including cells that cross the pallio-subpallial border.
TS22: thalamus Present Regionally restricted 3G Expression is to/from the thalamus including cells that cross the pallio-subpallial border.

Specimen 3H: embryonic day 14.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 3H Expression cells do not cross the pallio-subpallial border.

Specimen S4R: embryonic day 18.5; Vti1atm1Gfvm/Vti1a+, Vti1btm1Gfvm/Vti1b+ (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted S4R Expression is to/from the thalamus including cells that cross the pallio-subpallial border.
TS26: thalamus Present Regionally restricted S4R Expression is to/from the thalamus including cells that cross the pallio-subpallial border.

Specimen S4S: embryonic day 18.5; Vti1atm1Gfvm/Vti1atm1Gfvm, Vti1btm1Gfvm/Vti1btm1Gfvm (more )
Structure Level Pattern Image Note
TS26: cerebral internal capsule Present S4S
TS26: thalamus Present S4S


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory