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Gene Expression Data
Assay Details
Assay
Reference: J:18378 van Genderen C, et al., Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev. 1994 Nov 15;8(22):2691-703
Assay type: RNA in situ
MGI Accession ID: MGI:5641935
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Probe: GN8 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present 1A
TS20: inner ear Present 1A
TS20: midbrain Present 1A
TS20: tongue Present 1A
TS20: oral region Present Regionally restricted 1A Expression is in the upper and lower lip.
TS20: nasal process Present Regionally restricted 1A Expression is in the mesenchyme of the snout.
TS20: oral epithelium Present Regionally restricted 1A Expression is in dental placodes.
Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros Present 1B
TS22: midbrain Present 1B
TS22: pituitary gland Present 1B
TS22: tooth Present 1B
TS22: vibrissa Present 1B
Specimen 1C: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: oral region mesenchyme Present Regionally restricted 1C Expression is in the mesenchyme underlying the presumptive dental epithelium.
Specimen 1D: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: dental papilla Present 1D
TS22: tooth epithelium Present 1D
Specimen 1F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa Strong 1F
Specimen 1G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present 1G
TS20: trigeminal nerve Present 1G
Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 6A Ventral skin.
TS21: mammary gland primordium Present 6A
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Strong
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory