Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(ACTA1-DMD*)326Dua
Name:	transgene insertion 326, Dongsheng Duan
MGI ID:	MGI:5641706
Synonyms:	deltaR4-23/deltaC
Transgene:	Tg(ACTA1-DMD*)326Dua  Location: unknown
Alliance:	Tg(ACTA1-DMD*)326Dua page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(ACTA1-DMD*)326Dua expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human DMD (1756) Dmd  (MGI:94909) Full length human dystrophin cDNA is modified by the deletion of repeat 4 to 23 and the C-terminus.   Mutation details: The transgenic construct contains a full length human dystrophin gene modified by the deletion of repeat 4 through repeat 23 and the C-terminus to generate a micro-dystrophin cDNA (deltaR4-23/deltaC) under the control of the human skeletal alpha 1 actin (ACTA1) promoter. (J:167308)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:167308 Li D, et al., Nitrosative stress elicited by nNOSmicro delocalization inhibits muscle force in dystrophin-null mice. J Pathol. 2011 Jan;223(1):88-98
All:	4 reference(s)