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Gene Expression Data
Assay Details
Assay
Reference: J:132697 Torban E, et al., Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3449-54
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5641651
Gene symbol: Vangl1
Gene name: VANGL planar cell polarity 1
Reporter: lacZ
Direct Detection
Results
Specimen 2B: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2B
TS13: notochord Present 2B
Specimen 2C: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2C
TS13: notochord Present 2C
Specimen 2D: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2D
TS13: notochord Present 2D
Specimen 2E: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2E
TS13: notochord Present 2E
TS13: future hindbrain Strong Regionally restricted 2E Expression in the rostral hindbrain is in the ventral ventricular zone.
Specimen 2F: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2F
TS13: notochord Present 2F
TS13: rhombomere 4 Strong Regionally restricted 2F Expression is in the ventral and dorsal areas of the neural tube.
Specimen 2G: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2G
TS13: notochord Present 2G
TS13: neural tube Present 2G At the level of neural tube closure the entire neural tube is positive for expression.
Specimen 2H: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2H
TS13: notochord Present 2H
TS13: neural tube roof plate Present Regionally restricted 2H In more caudal regions expression is in a few cells near the junction point of opposed neural folds.
Specimen 2J: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: neural tube Trace 2J Most expression disappeared in the closed neural tube.
TS15: heart Trace 2J
TS15: limb mesenchyme Present 2J
Specimen 2K: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: neural tube Trace 2K Most expression disappeared in the closed neural tube.
TS15: limb mesenchyme Present 2K
Specimen 2L: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 2L
TS13: notochord Present 2L
Specimen 2M: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: neural tube roof plate Present Single cells 2M
Specimen 2N: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: notochord Strong 2N
Specimen 2O: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: heart Present 2O
Specimen 2P: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS15: notochord Present 2P
TS15: nephric duct Present Regionally restricted 2P Expression is in the mesoneprhic duct.
Specimen 6A: embryonic day 10.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS17: 4th arch artery Present 6A
TS17: heart Present 6A
Specimen 6B: embryonic day 10.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS17: heart Present 6B
Specimen S8D: embryonic day 14.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted S8D Expression is in the organ of Corti.
Specimen not shown: embryonic day 13.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg (more )
Structure Level Pattern Image Note
TS21: notochord Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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