About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:219860 Chassefeyre R, et al., Regulation of postsynaptic function by the dementia-related ESCRT-III subunit CHMP2B. J Neurosci. 2015 Feb 18;35(7):3155-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641374
Gene symbol: Chmp2b
Gene name: charged multivesicular body protein 2B
Antibody: anti-Chmp2b (ab33174)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was 4% formaldehyde with 0.05% glutaraldehyde. Vibratome sections.
Results
Specimen 1D left: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 1D left
TS28: habenula Strong 1D left
TS28: hippocampus Strong 1D left
TS28: main olfactory bulb Strong 1D left
TS28: neocortex Strong Regionally restricted 1D left Expression is in the deep layers.
Specimen 1D right: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 1D right
TS28: habenula Strong 1D right
TS28: hippocampus Strong 1D right
TS28: main olfactory bulb Strong 1D right
TS28: neocortex Strong Regionally restricted 1D right Expression is in the deep layers.
Specimen 1E left: postnatal adult (more )
Note: The right panel is a higher magnification of the boxed area in the left panel.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1E right , 1E left Expression is in the somatodendritic compartment of numerous neurons.
Specimen 1F Wt: postnatal week 5 (more )
Structure Level Pattern Image Note
TS28: brain Present 1F Wt
Specimen 1F KD: postnatal week 5; Chmp2bGt(XL952)Byg/Chmp2bGt(XL952)Byg (more )
Structure Level Pattern Image Note
TS28: brain Weak 1F KD
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory