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Tg(Gnrhr-luc/EGFP)L8Mrln
Transgene Detail
Summary
Symbol: Tg(Gnrhr-luc/EGFP)L8Mrln
Name: transgene insertion L8, Glenn Merlino
MGI ID: MGI:5641258
Synonyms: GH, Glowing Head, rGH-ffLuc-eGFP
Transgene: Tg(Gnrhr-luc/EGFP)L8Mrln  Location: unknown  
Alliance: Tg(Gnrhr-luc/EGFP)L8Mrln page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgenic construct contains a firefly luciferase (ffLuc)-eGFP fusion gene under the control of the rat growth hormone gene promoter and human growth hormone sequences. Reporter activity (by bioluminescent imaging) is detected in the anterior pituitary gland and testes. (J:221565)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:221565 Day CP, et al., "Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts. PLoS One. 2014;9(11):e109956
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory