Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Rho*)5PRieke
Name:	transgene insertion 5P, Fred Rieke
MGI ID:	MGI:5641078
Synonyms:	S343A
Transgene:	Tg(Rho*)5PRieke  Location: unknown
Alliance:	Tg(Rho*)5PRieke page

Strain of Origin:

(C57BL/6J x DBA/2J)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutations:    Insertion, Nucleotide substitutions   Tg(Rho*)5PRieke expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Rho (MGI:97914)   Mutation details: The transgene expresses mouse Rho carrying S334, T336, S338, T340, and T342 phosphorylation sites. The remaining phosphorylation sites in the Rho transgene, S343, is inactivated via a serine to alanine mutation. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin. (J:188325)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:188325 Mendez A, et al., Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron. 2000 Oct;28(1):153-64
All:	3 reference(s)