Tg(Rho*)2PRieke
Transgene Detail
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Symbol: |
Tg(Rho*)2PRieke |
Name: |
transgene insertion 2P, Fred Rieke |
MGI ID: |
MGI:5640778 |
Synonyms: |
2P, S334/S338/CSM |
Transgene: |
Tg(Rho*)2PRieke Location: unknown
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Alliance: |
Tg(Rho*)2PRieke page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutations: |
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Insertion, Nucleotide substitutions
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Tg(Rho*)2PRieke expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Rho (MGI:97914) |
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Mutation details: The transgene expresses mouse Rho carrying only the S334 and S338 phosphorylation sites. The remaining phosphorylation sites in the Rho transgene (T336, T340, T342 and S343) are inactivated via serine or threonine to alanine mutations. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin.
(J:188325)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:188325 Mendez A, et al., Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron. 2000 Oct;28(1):153-64 |
All: |
3 reference(s) |
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