Gene Expression Data
Assay Details
Assay
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Reference:
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J:160540
Wang J, et al., Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9753-8
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5639310
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Gene symbol:
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Hcn4
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Gene name:
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hyperpolarization-activated, cyclic nucleotide-gated K+ 4
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Probe:
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Hcn4 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3Ca:
embryonic day 12.5
(more )
Specimen
3Ca:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
S4A:
embryonic day 12.5
(more )
Specimen
S4A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
S4B:
embryonic day 12.5
(more )
Specimen
S4B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
3Cb:
embryonic day 12.5; Pitx2tm1Jfm/Pitx2 +
(more )
Specimen
3Cb:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS20: vena cava |
Present |
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3Cb
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Expression modestly upregulated in the left superior caval vein.
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Specimen
S4C:
embryonic day 12.5; Pitx2tm1Jfm/Pitx2 +
(more )
Specimen
S4C:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
S4D:
embryonic day 12.5; Pitx2tm1Jfm/Pitx2 +
(more )
Specimen
S4D:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
3Cc:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2tm1Jfm
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS20: left atrium |
Present |
Regionally restricted |
3Cc
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Authors report continuous expression in abnormal vein-atrial junction and posterior wall of left atrium.
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TS20: vena cava |
Present |
Regionally restricted |
3Cc
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Authors report continuous expression in abnormal vein-atrial junction and posterior wall of left atrium.
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Specimen
S4E:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2tm1Jfm
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
S4F:
(close )
Genetic Background:
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involves: 129S4/SvJaeSor
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Mutant Allele(s):
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Pitx2tm1Jfm/Pitx2tm1Jfm
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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