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Gene Expression Data
Assay Details
Assay
Reference: J:160540 Wang J, et al., Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9753-8
Assay type: RNA in situ
MGI Accession ID: MGI:5639310
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Probe: Hcn4 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3Ca: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vena cava Present 3Ca Expression in large caval veins posterior to the heart.
TS20: sinoatrial node Present 3Ca

Specimen S4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinoatrial node Present S4A
TS20: sinus venosus Present S4A

Specimen S4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinoatrial node Present S4B

Specimen 3Cb: embryonic day 12.5; Pitx2tm1Jfm/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: vena cava Present 3Cb Expression modestly upregulated in the left superior caval vein.

Specimen S4C: embryonic day 12.5; Pitx2tm1Jfm/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: sinoatrial node Present S4C
TS20: vena cava Present S4C

Specimen S4D: embryonic day 12.5; Pitx2tm1Jfm/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: sinoatrial node Present S4D

Specimen 3Cc: embryonic day 12.5; Pitx2tm1Jfm/Pitx2tm1Jfm (more )
Structure Level Pattern Image Note
TS20: left atrium Present Regionally restricted 3Cc Authors report continuous expression in abnormal vein-atrial junction and posterior wall of left atrium.
TS20: vena cava Present Regionally restricted 3Cc Authors report continuous expression in abnormal vein-atrial junction and posterior wall of left atrium.

Specimen S4E: embryonic day 12.5; Pitx2tm1Jfm/Pitx2tm1Jfm (more )
Structure Level Pattern Image Note
TS20: vena cava Present S4E

Specimen S4F: embryonic day 12.5; Pitx2tm1Jfm/Pitx2tm1Jfm (more )
Structure Level Pattern Image Note
TS20: vena cava Present S4F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory